منابع مشابه
Natural peptides and proteins: potent tyrosinase inhibitors
Background and objectives: Tyrosinase is a copper containing oxidase which is crucial for controlling the production of melanin in creatures such as bacteria, fungi, plants and mammals. It is involved in the first two steps of melanin biosynthesis and leads to pigmentation and different types of cancer such as melanoma. Also, it is responsible for browning of fruits and vegetab...
متن کاملHuman Antimicrobial Peptides and Proteins
As the key components of innate immunity, human host defense antimicrobial peptides and proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition, AMPs can possess other biological functions such as apoptosis, wound healing, and immune modulation. This article provides an overview on the identification, activity, 3D structure, and mechanism of action of human...
متن کاملHPLC of peptides and proteins.
High-performance liquid chromatography (HPLC) is an essential tool for the purification and characterization of biomacromolecules. This unit presents a thorough discussion of the eight types of HPLC currently used, highlighting equipment and start-up procedures, recommendations for running each type of experiment, and theoretical considerations for the separation of peptides and proteins. This ...
متن کاملThe selective S-methylation of sulfhydryl groups in proteins and peptides with methyl-p-nitrobenzenesulfonate.
The cysteine residues in proteins and peptides may be quantitatively and selectively converted to the S-methyl derivatives by reaction with methyl-p-nitrobenzenesulfonate. Procedures are described for the reduction and methylation of a variety of proteins at pH 8.6 and 37”, together with the pH rate profile for the methylation of reduced glutathione at 25”. The methylation of S-sulfoinsulin B c...
متن کاملP135: The Role of Amyloid Beta-Peptides and Tau Protein in Alzheimer\'s Disease
Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms. Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...
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ژورنال
عنوان ژورنال: Biochemistry and Molecular Biology Education
سال: 2003
ISSN: 1470-8175,1539-3429
DOI: 10.1002/bmb.2003.494031040234